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NEW QUESTION: 1
A 55-year-old female is receiving chemotherapy for metastatic carcinoma. She threatens to stop her treatment because of severe nausea and vomiting. The oncologist plans to use prochlorperazine to reduce the nausea and vomiting associated with chemotherapeutic agents. What is the mechanism of action of prochlorperazine?
A. Serotonin 5-HT3 antagonist
B. Blockage of prostaglandins
C. Blocking dopamine receptors
D. H2 receptor antagonist
E. Cannabinoids related
Answer: C
Explanation:
Explanation
B: A variety of drugs have been found to be of some value in the prevention and treatment of vomiting, especially cancer chemotherapy-induced vomiting. With the exception of thioridazine, most of the neuroleptic drugs have antiemetic effects that are mediated by blocking D2 dopaminergic receptors of the chemoreceptor trigger zone of the medulla. Phenothiazines, such as prochlorperazine, were the first drugs shown to be effective antiemetic agents and act by blocking dopamine receptors. They are effective against low to moderately emetogenic chemotherapeutic agents (for example, fluorouracil and doxorubicin). Although increasing the dose improves antiemetic activity, side effects, including hypotension and restlessness, are dose limiting. Other adverse reactions include extrapyramidal symptom and sedation. A: Serotonin 5-HT3 antagonist is incorrect. The specific antagonists of the 5-HT3 receptor, ondansetron and granisetron, selectively block 5-HT3 receptors in the periphery and in the brain (chemoreceptor trigger zone). C:
Cannabinoids related is incorrect. Cannabinoids are marijuana derivatives including dronabinol and nabilone and are effective against moderately emetogenic chemotherapy. However, they are seldom first-line antiemetics because of serious side effects. D: Blockage of prostaglandins is incorrect. Dexamethasone and methylprednisolone used alone are effective against mildly to moderately emetogenic chemotherapy. Their antiemetic mechanism is not known, but it may involve blockade of prostaglandins. E: H2 receptor antagonist is incorrect. Antagonists of histamine H2 receptor block the action of histamine at all H2 receptors; their chief clinical use is as inhibitors of gastric acid secretion.

NEW QUESTION: 2
Refer to the exhibit.

To allow the System Manager to manage bandwidth on the Avaya Aura@ Conferencing SIP Entity, which field must be selected?
A. Shared Bandwidth Manager
B. Supports Call Admission Control
C. SIP Link Monitoring
D. Primary Session Manager Bandwidth Association
Answer: B

NEW QUESTION: 3




Which four levels of messages will be sent to the logging server? (Choose four.)
A. errors
B. alerts
C. debugging
D. warnings
E. notifications
F. informational
G. critcal
H. emergencies
Answer: A,B,G,H

NEW QUESTION: 4
A software vendor-provided best practice should be adhered to ___________. (Choose two)
A. at all times because the vendor wrote and designed the software
B. in the absence of other requirements as a guide to configuration
C. where possible, respecting other project requirements
Answer: B,C
Explanation:
A best practice is based on experience with delivering a solution. A new product will have limited best-practice information except for vendor- or vendor-partner-based recommendations. The longer a technology is used in a community, the more potential success; therefore, best practices may change over time. Chapter 6, Validation, Thoughts, and Processes